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High Purity Human Growth Factor Protein Promoting Epidermal Cell Growth

Categories Epidermal Growth Factor
Brand Name: Oryzogen
Model Number: HY203M1
Certification: ISO9001 certificate
Place of Origin: China
MOQ: Negotiation
Price: Negotiation
Payment Terms: T/T
Supply Ability: 1kg per year
Delivery Time: 3-5 days
Packaging Details: 1mg/vial 10mg/vial
Source: Rice Grain
Endotoxin: Less than 5EU/mg
ED50: ≤1ng/ml
Storage and Handling: -20℃ for 12 months
Molecular Weight: 6.3kD
Production Type: Recombinant protein
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    High Purity Human Growth Factor Protein Promoting Epidermal Cell Growth

    High Purity Human Growth Factor Protein Promoting Epidermal Cell Growth


    Description

    Epidermal cells are always used in the research for the skin cell metabolism and regeneration. EGF is an important growth factor for stimulating epithelial cells growth and promoting the new epidermis cells constantly to ripen. At the same time, EGF accelerate the metabolism of skin cells, enhance the absorption of nutritions; EGF promote the synthesis of collagen and collagenase and the secretion of collagen substances, hyaluronic acid and glycoprotein. So rEGF always used in the epidermal cell culture.


    Quick detail

    1. CAS No.: 62229-50-9
    2. Other Names: rEGF
    3. EINECS No.: 263-468-7
    4. Brand Name: Oryzogen
    5. Model Number: HY203M1
    6. Purity: Greater than 95 % as determined by SDS-PAGE
    7. Physical Appearance: white lyophilized powder
    8. Formulation: rEGF is lyophilized with mannitol as the stabilizer

    Physiological and Biochemical Properties of our rEGF and rEGF(E.coli)

    Char.rEGFrEGF(E.coli)
    Amino Acids SequenceSameSame
    N-terminusASTPGASTPG
    C-terminusALGTTALAATGALGTTALAATG
    Molecular Mass(MALDI)6.3KD6.3KD
    Bioactivity>1*106IU/mg>1*106IU/mg
    Purity>98%>95%
    Endotoxin<5EU/mg<10EU/mg


    Advantages

    1. Healthgen recombinant Epidermal Growth Factor (rEGF) has excellent batch consistency. Using self-pollination rice as the bioreactor to express the rEGF with the world's advanced facility and top production proceeding to extract and purify the rHSA, Healthgen can ensure the excellent consistency of rEGF from different batches.


    2. The rice endosperm specific expression platform is easy to be large-scale. The rice endosperm has the protein body, which can keeps proteins stability and bioactivity. At present, the production capacity is almost 1 kg / year.


    3. Healthgen has a professional quality control department, in which 50% of them have master's degree or higher. There are 14 employees in the quality department, 9 of them are in QA and 5 are in QA. All of them have rich experience in analysis research or quality inspection. Half of them have graduated diploma. Every year there are more than 50 training courses, which cover GMP, SOP, specification, hygiene, QA, QC issues, etc.


    Supplemental Description

    EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant human EGF is a 6.2 kDa globular protein containing 53 amino acid residues including 3 intramolecular disulfide-bonds. Manufactured using all non-animal reagents.

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